[ Instrument Network Instrument Development ] Single-cell sequencing technology is a technique for high-throughput sequencing analysis of genomes, transcriptomes, and epigenetic groups at the single-cell level. Single-cell sequencing technology can reveal intercellular heterogeneity at the omics level. The single-cell level cell lineage tracking technology ranks first among the top 10 scientific breakthroughs in the 2018 Science magazine. Conventional single-cell transcriptome sequencing technology loses spatial location information critical to the cell in the original tissue, while single-cell spatial transcriptome technology preserves and records spatial location information of cells while performing single-cell transcriptome sequencing. Spatial transcriptome technology can reveal the interaction between cells and the microenvironment in which cells are located. It will become a research tool in the fields of developmental biology, neurobiology, immunobiology, and tumor microenvironment.
On November 12th, Nucleic Acids Research published a paper on the high-throughput sequencing center of the Institute of Biophysics of the Chinese Academy of Sciences entitled SpatialDB: a database for spatially resolved transcriptomes, releasing the first single-cell spatial transcriptome. Database and data online visualization platform. The SpatialDB system includes data from eight spatial transcriptome technologies from five species, establishes a spatial transcriptome data analysis process, and realizes online visualization of spatial transcriptome data, while providing spatially differentially expressed genes and their functional richness. Set the comments for the analysis.
Academician of the Chinese Academy of Sciences, researcher Chen Runsheng of the Institute of Biophysics, and senior engineer Chen Xiaowei are co-authors of the paper. Fan Zhen, senior engineer of the High-throughput Sequencing Center of Biophysics, is the first author of the paper. The research was funded by the Chinese Academy of Sciences key technical talent project, the National Natural Science Foundation and national key research and development projects.
Vacuum Formed Toys
Vacuum forming process is used to produce a variety of parts and components for toys and hobby products, including model cars, airplanes, children drones,and boats. The process allows for the creation of intricate shapes and designs at a relatively low cost.
The characteristics of vacuum forming toys:
1.Lightweight: Vacuum-formed toys are typically lightweight, making them easy for children to handle and play with.
2.Durable: Vacuum-formed toys are made from sturdy materials such as plastic, which makes them durable and able to withstand rough play.
3.Various types and colors. As custom vacuum formed,the toys can be with various types and colors.
4.Cost-effective: Vacuum forming is a cost-effective manufacturing process, making vacuum-formed toys affordable for consumers.
5.Safe: Vacuum-formed toys are typically designed with rounded edges and non-toxic materials, ensuring the safety of children during play
6.Easy to clean: Vacuum-formed toys are easy to clean and maintain, as they can be wiped down with a damp cloth or washed with mild soap and water.
7.Eco-friendly: Vacuum-formed toys can be done using recyclable materials which is environmentally friendly.
