Apixaban API And Intermediates
Apixaban is a novel oral factor Xa inhibitor jointly developed by Bristol-Myers Squibb and Pfizer under the trade name Aldol, which is a novel oral anticoagulant. Apixaban prevents thrombin production and thrombosis by inhibiting an important clotting factor, Xa. On April 26, 2007, Bristol-Myers Squibb and Pfizer announced a collaboration to develop apaxaban, a new oral anticoagulant owned by BRIstol-Myers Squibb, as an upgraded alternative to warfarin. Under the agreement, Pfizer will make an upfront payment of $250 million to Bristol-Myers Squibb for 60 percent of the total development cost of apisaban, effective January 1, 2007, and Bristol-Myers Squibb will pay the remaining 40 percent, resulting in co-development and marketing rights for the drug. In May 2011, Apixaban was approved for the prevention of venous thrombosis in adults undergoing elective hip or knee replacement surgery in 27 European Union countries, Iceland and Norway. On 20 November 2012, the European Commission approved aldol (apisaban) for the prevention of stroke and systemic circulation embolism in adult patients with NVAF who have one or more risk factors for wind Chemicalbook. Subsequently, FDA of Canada, Japan and the United States approved Aldol? Apixaban is indicated for the prevention of stroke and systemic circulation embolism in adult patients with nonvalvular atrial fibrillation (NVAF) with one or more risk factors. On April 12, 2013, ELIQUIS (apisaban), a new Anticoagulant Drug jointly developed by Bristol-Myers Squibb and Pfizer, was officially launched in China. Aldol is a novel oral factor Xa inhibitor for the prevention of venous thromboembolism (VTE) in adult patients undergoing elective hip or knee replacement. Its marketing provides a safe and effective new alternative for clinical anticoagulation after orthopedic surgery, and brings good news to patients undergoing elective hip/knee replacement in China. Clinical studies have demonstrated that two oral doses of enoxaparin per day are better than one subcutaneous injection of enoxaparin 40mg per day. Apixaban 2.5mg is more effective in preventing venous thromboembolic events after hip or knee replacement surgery without increasing the risk of bleeding.
China Apixaban Cas 38560-30-4,Apixaban Cas 503615-03-0,Apixaban Cas 881386-01-2 ,Apixaban Cas 1267610-26-3,Apixaban Cas 536760-29-9,Apixaban Cas 545445-44-1,Good Stock Apixaban API Cas 503612-47-3,Commercial Apixaban BMS 562247-01,Best Quality Apixaban Eliquis etc.
China Apixaban Cas 503612-47-3,Apixaban Cas545445-44-1,Apixaban Cas 38560-30-4,Apixaban Cas 881386-01-2,Apixaban Cas 503615-03-0,Apixaban Cas 1267610-26-3 Supplier  Shandong Haohong Biotechnology Co., Ltd. , https://www.haohongpharma.com
YS200B Starway Warning high quality Car siren horn speaker for policeÂ
1.Summary
- This Starway Warning horn siren speaker(YS100D) is characterized by its high intensity, waterproof, dampproof, durable and energy saving also it is adopted quality alnico, andÂ
- Â It is provide with high efficiency conversion, high-pitched advamce technics, nicer making, high dependability.Â
- This Srien Speaker is fitted for same power sirens.Â
- Siren speaker can be directly used conneting electronic source, and with some tones.
2.Features:
 1) Out Power:200W
 2) Sound Pressure:122-125DB
 3) Impedance:4 ohm or 8 ohmÂ
 4) Weather-proof housing
 5) Fitted for 200W Siren
 6) Magnetic: NdFeB insideÂ
 7) Net Weight:3.35KGS
 8)Usage:Most kind of Car
Â
YS200B Starway Warning high quality Car siren horn speaker for policeÂ
1.Summary
- This Starway Warning horn siren speaker(YS100D) is characterized by its high intensity, waterproof, dampproof, durable and energy saving also it is adopted quality alnico, andÂ
- Â It is provide with high efficiency conversion, high-pitched advamce technics, nicer making, high dependability.Â
- This Srien Speaker is fitted for same power sirens.Â
- Siren speaker can be directly used conneting electronic source, and with some tones.
2.Features:
 1) Out Power:200W
 2) Sound Pressure:122-125DB
 3) Impedance:4 ohm or 8 ohmÂ
 4) Weather-proof housing
 5) Fitted for 200W Siren
 6) Magnetic: NdFeB insideÂ
 7) Net Weight:3.35KGS
 8)Usage:Most kind of Car
Â
Model NO.: YS200B
Magnetic: NdFeB InsideÂ
Usage: Most Kind of Car
Trademark: Starway
Transport Package: Exporting Carton
Specification: 159*156*70mm
Origin: China
Model NO.: YS200B
Magnetic: NdFeB InsideÂ
Usage: Most Kind of Car
Trademark: Starway
Transport Package: Exporting Carton
Specification: 159*156*70mm
Origin: China